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In one embodiment, an anti-solvent is added to a solution to decrease its solubility for a particular compound, thus resulting in precipitation.

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Letermovir: Moderate An increase in the plasma concentration of tadalafil may occur if given sexual letermovir. In patients who are also receiving treatment with cyclosporine, the magnitude of this interaction may be amplified.

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The interaction of tadalafil with alcohol was evaluated in 3 clinical pharmacology studies. In 2 of these, alcohol was administered at a dose of 0. In one of these two studies, blood alcohol levels of 0.

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